Regular services will begin operating on March 24, with intermediate stops at Düsseldorf, Duisburg, Essen, Gelsenkirchen, Münster and Osnabrück.
The route was formerly served by Hamburg-Cologne Express, which suspended operations last year.
GERMAN open-access operator FlixTrain launched its first services on March 23, when an inaugural train left Hamburg Altona at 08.36 bound for Cologne.
Regular services will begin operating on March 24, with intermediate stops at Düsseldorf, Duisburg, Essen, Gelsenkirchen, Münster and Osnabrück.
The route was formerly served by Hamburg-Cologne Express, which suspended operations last year.