Two services a day now link Venice, Padova, Bologna Central, and Florence Santa Maria Novella (SMN) with the airport, running via Rome's Tiburtina and Termini stations. The service offers journey times of 4h 12min from Venice Mestre, 2h 59min from Bologna Central, and 2h 14min from Florence SMN.

The new service is intended to complement the Fiumicino - Termini Leonardo Express and FL1 Fiumicino - Ostiense - Tiburtina services.

For the time being the airport can only be served by seven-car Frecciaargento trains due to the short platforms at Fiumicino and the services run via the conventional line from Rome, although there are plans to construct a dedicated high-speed line to the airport.

By the end of this year Italian infrastructure manager RFI will present the feasibility studies for high-speed connections to Fiumicino, Milan Malpensa and Venice Marco Polo airports.

In 2012 Trentialia signed an agreement with fare transaction processor Amadeus, enabling passengers from anywhere in the world to make combined air/rail bookings onto Trenitalia high-speed services through the Amadeus FlyByRail Track system.