From December 10, northbound services will depart from Karlovy Vary Dolní Nádraží at 06.48 and 14.41, arriving at Zwickau Main Station at 08.59 and 16.59 respectively. Both services offer a five-minute connection with S-Bahn services to Leipzig and Halle. Southbound trains will depart from Zwickau at 10.03 and 18.03.

The service will be operated by GW Train Regio, Czech Republic, and will require a subsidy of around €6m per year from the regional government.